Improving the tolerability of antiseizure medications: When and how to use cenobamate and other new antiseizure medications

Despite the introduction of newer antiseizure medications (ASMs) with improved safety profiles over the past several years, rates of treatment-related intolerable adverse events (AEs) for people with epilepsy have not changed substantially. Tolerability issues can potentially jeopardize optimal dosing and effectiveness, regimen adherence, and treatment retention with these newer medications. Long-term clinical studies, open-label extension […]

“How-to”: scoping review? – PubMed

Background and objective: Scoping reviews are a type of evidence synthesis that aims to identify and map the breadth of evidence available on a particular topic, field, concept, or issue, within or across a defined context or contexts. Scoping reviews can contribute to clinical practice guideline development, policy making, reduce research waste by eliminating duplication […]

Shark attacks: Expert’s advice on how to coexist in NZ waters this summer

“It’s just tragic. It’s the worst thing that can happen to a family, a person, or a community,” said shark expert Dr Riley Elliott. “While shark attacks are statistically improbable, they are always tragic and should not be undermined.” Kahukore-Dixon’s death was different from the other recent fatal attacks, as it happened in the remote […]