“How-to”: scoping review? – PubMed

Background and objective: Scoping reviews are a type of evidence synthesis that aims to identify and map the breadth of evidence available on a particular topic, field, concept, or issue, within or across a defined context or contexts. Scoping reviews can contribute to clinical practice guideline development, policy making, reduce research waste by eliminating duplication […]

How to Design an Inhaled Drug: CHF-6523

Inhalation provides an opportunity to target drugs to the lung, potentially improving efficacy and safety margins for the treatment of respiratory conditions. The discovery of inhaled medicines is a specialized endeavor and has different challenges to medicinal chemistry for oral drugs. The appearance of a successful campaign delivering an inhaled PI3Kδ inhibitor is therefore an […]

How to talk to parents

Review doi: 10.1007/s00247-024-06146-6. Online ahead of print. Affiliations Expand Affiliations 1 Paediatric and prenatal radiology department, Hôpital Timone Enfants, APHM, 264 rue Saint Pierre, Marseille, 13005, France. [email protected]. 2 Paediatric and prenatal radiology department, Hôpital Timone Enfants, APHM, 264 rue Saint Pierre, Marseille, 13005, France. Item in Clipboard Review Antoine Martin-Champetier et al. Pediatr Radiol. 2025. […]

How to do a hip disarticulation

Case Reports doi: 10.1111/ans.19330. Online ahead of print. Affiliations Expand Affiliations 1 Department of Burns, Plastic & Maxillofacial Surgery, Royal North Shore Hospital, Sydney, New South Wales, Australia. 2 Northern Clinical School, University of Sydney, Sydney, New South Wales, Australia. Item in Clipboard Case Reports Yewon David Kim et al. ANZ J Surg. 2024. Show details […]

Femoral Large Bore Sheath Management: How to Prevent Vascular Complications From Vessel Puncture to Sheath Removal

Transfemoral access is nowadays required for an increasing number of percutaneous procedures, such as structural heart interventions, mechanical circulatory support, and interventional electrophysiology/pacing. Despite technological advancements and improved techniques, these devices necessitate large-bore (≥12 French) arterial/venous sheaths, posing a significant risk of bleeding and vascular complications, whose occurrence has been related to an increase in […]