What does the latest research say about how to reduce dementia risk?

You may be aware that smoking, lack of exercise, poor diet and too much alcohol are linked to dementia and stroke.

But there are some other, perhaps surprising, ways you can reduce your risk of cognitive impairment as you age.

Sleep, socialising, challenging your brain, and small amounts of alcohol have all been found to improve brain health.

Neuroscience Research Australia chief executive and Brain Foundation president Matthew Kiernan takes us through the latest research, and we hear from people who are trying to reduce their dementia risk.

Let’s start with a good sleep

Scientists have become more aware of the importance of sleep on brain health in recent years.

During deep sleep the glymphatic system is activated.

“This is really a reservoir that puts all of the fluid through the brain and cleans out toxic chemicals,” Professor Kiernan said.

“It only becomes active when we’re in the deepest REM (rapid eye movement) sleep”

Professor Kiernan said it was important to get between six and eight hours of sleep a night.

The Brain Foundation suggests staying off your phone and not looking at work emails after 9pm, that you stop drinking caffeine after midday and not going to bed until you feel sleepy.

Socialising and challenging your brain

Katrina Coleman is doing her brain a favour with a group jigsaw puzzle session.

Ms Coleman won a national puzzle championship and came 20th in the World Jigsaw Puzzle Championships in Spain last year.

She’s known about the importance of challenging her brain since she was a child.

“My grandmother used to do a lot of crosswords as well as the puzzles and she had a very active brain right up until she passed,” Ms Coleman said.

Adding a social element to puzzling is a new thing.

“If you can socialise with other people while doing your puzzles you can reduce anxiety levels and keep that social interaction happening particularly as you get a little bit older,” Ms Coleman said.

According to the Brain Foundation, cognitive functioning decreases with age because of a loss of connective structures called synapses.

Like any other muscle, the connections in the brain need to be used and challenged to stay strong.

Professor Kiernan said that could mean trying new things like going to the theatre, travelling, reading or doing crosswords.

He said while socialising was also incredibly important for the brain, it’s not clear why it works.

“Maybe it’s through the release of other neurotransmitters in the brain, including oxytocin and dopamine, that enhance brain function longer term,” Professor Kiernan said.

Alcohol and HRT

There’s new evidence that hormone replacement therapy (HRT) may reduce the risk of Alzheimer’s disease in women.

A study recently published in the journal Frontiers in Aging Neuroscience has found that estrogen therapy could protect the female brain from Alzheimer’s and dementia if the hormones were taken when menopausal symptoms began.

Professor Kiernan said the results from the large-scale study were promising.

“That’s something that’s cutting edge and obviously needs to be explored in greater detail,” he said.

Previous studies have shown that beginning HRT later in life could carry a greater risk of developing dementia.

The Australian Menopause Society stated there was weight to the “timing theory” which suggested initiation of hormone therapy around the time of menopause may have health benefits, whereas beginning the therapy later in life carried greater risk.

There was also a sweet spot when it came to alcohol consumption. Small amounts of alcohol can improve cognitive function long term, Professor Kiernan said.

“Particularly red wine which may be through antioxidant and vasodilator effects.”

But he said intake must be limited.

“That means basically one or two standard drinks per day … and less than 10 alcoholic drinks per week.”

Jon’s story

Jon Moore’s mother had dementia.

“She passed away at quite an early age,” Mr Moore said.

“It’s amazing the effect it has on you, and it’s a very sad thing, sad for the person and very hard for the family.”

Mr Moore is participating in what’s been described as the world’s largest dementia prevention study.

The study is called the Island Project, and it’s run by the Wicking Dementia Centre in Tasmania.

The project is looking to sign up more than 20,000 people aged over 50 years to take part in the study.

It involved participants doing a series of online tasks and movements, like tapping their fingertips.

Artificial intelligence is used to determine if there might be subtle changes in some of those movements which might indicate changes in brain function.

The Wicking Centre’s James Vickers said those subtle changes could indicate a neurodegenerative process “years before you start to develop symptoms, the obvious symptoms of dementia”.

Professor Vickers said these early indications could give participants a chance to slow or prevent the onset of dementia by making lifestyle changes.

That could mean addressing issues like obesity, smoking and high blood pressure.

While most of the risk for dementia was associated with ageing, research has shown about a third of dementia cases could be prevented if risk factors were addressed, particularly from middle age onwards.

Professor Vickers said there were risks people may not be aware of yet.

“Depression in older age is linked to risk of dementia,” he said.

“Educational attainment is an interesting one; the more education you have earlier in your life the less chance you have of developing dementia later in your life.”

If this story prompts any questions or concerns, you can contact the 24/7 National Dementia Helpline on 1800 100 500 or visit dementia.org.au.

LoadingLoading…