Declaration of competing interest Christian Bork reports travel was provided by European Atherosclerosis Society and fundings grants outside the submitted work from the Karen Elise Jensens Foundation and the Novo Nordic Foundation. Børge G. Nordestgaard reports a relationship with AstraZeneca, Sanofi, Ionis, Amgen, Amarin, Novartis, Novo Nordisk, Esperion, Lilly, Arrowhead, Marea, MSD that includes consulting or advisory. President of the European Atherosclerosis Society. Berit Storgaard Hedegaard reports relationships with Novartis and AMGEN that includes speaking and lecture fees and travel reimbursement, and with Chiesi Pharmaceuticals Inc that includes consulting or advisory and reports travel was provided by European Atherosclerosis Society. Michal Vrablik reports travel was provided by European Atherosclerosis Society. Tomas Freiberger reports a relationship with Next Generation European Union that includes funding grants. Zlatko Fras reports a relationship with Novartis Amgen Inc that includes: consulting or advisory, funding grants, and speaking and lecture fees and with Swixx Biopharma AG that includes consulting or advisory and speaking and lecture fees. Reports financial support and travel were provided by European Atherosclerosis Society. Reports a relationship with KRKA dd that includes funding grants and speaking and lecture fees. David Nanchen a relationship with European Atherosclerosis Society that includes travel reimbursement. Reports collaboration as an investigator in clinical studies sponsored by Amgen, Daiichi Sankyo, Pfizer and Novartis. He has not received any personal payments, either in cash or in kind, from these companies. Fouzia Sadiq reports administrative support, article publishing charges, travel, and writing assistance were provided by European Atherosclerosis Society. Kausik K Ray reports a relationship with Daiichi Sankyo Inc and Sanofi Aventis France that includes: consulting or advisory, funding grants, and speaking and lecture fees. Reports a relationship with New Amsterdam Pharma and Scribe Therapeutics Inc that includes consulting or advisory and equity or stocks. Kausik Ray reports a relationship with Novo Nordisk, Astra Zeneca, Menarini and Xeedia Pharma that includes consulting or advisory and speaking and lecture fees. Reports a relationship with Nodthera Limited, Eli Lilly and Company and Merck Sharp & Dohme UK Ltd that includes consulting or advisory. Reports a relationship with USV Pharma, Torrent Pharmaceuticals Limited and Algorithm Pharmaceutical Manufacturers that includes speaking and lecture fees. Reports a relationship with Ultragenix that includes funding grants and with Amarin Pharma Inc that includes: funding grants and speaking and lecture fees. Reports a relationship with PEMI 31 that includes equity or stocks. Kirsten B. Holven reports a relationship with European Atherosclerosis Society that includes: board membership, speaking and lecture fees, and travel reimbursement. Jeanine E. Roeters van Lennep reports a relationship with Novartis Pharmaceuticals Corporation that includes: funding grants paid to Erasmus MC. Ulrich Laufs reports a relationship with Amgen, Daiichi Sankyo, Novartis and Sanofi that includes consulting or advisory, speaking and lecture fees and research grants to Leipzig University. Evangelos Liberopoulos reports a relationship with ASTRA-ZENECA, Pharmaserve – Lilly, AMGEN, Sanofi, Viatris, BOEHRINGER-INGELHEIM, Novartis, SERVIER, CHIESI, NOVO NORDISK, KRKA and MENARINI that includes: speaking and lecture fees. Katariina Öörni reports to be Co-Editor of Atherosclerosis. Meral Kayikcioglu reports a relationship with Chiesi Pharmaceuticals Inc and Recordati Industria Chimica e Farmaceutica SpA that includes consulting or advisory, speaking and lecture fees, and travel reimbursement. Reports a relationship with Ultragenyx Pharmaceutical Inc and LIB Thera that includes: speaking and lecture fees. Reports a relationship with Abbott Cardiovascular that includes: consulting or advisory and speaking and lecture fees. Reports a relationship with Amgen Inc that includes: speaking and lecture fees and travel reimbursement. Executive Board Member of European Atherosclerosis Society. Mutaz Al-Khnifsawi reports a relationship with Chiesi Pharmaceuticals GMBH that includes consulting or advisory. Marianne Becker reports a relationship with Novo Nordisk that includes: speaking and lecture fees and travel reimbursement. Christoph J. Binder reports a relationship with Novartis, Amgen, Sanofi, SOBI that includes: consulting or advisory, speaking and lecture fees, and travel reimbursement. Given his role as co-editor of Atherosclerosis, he had no involvement in the peer review of this article and had no access to information regarding its peer review. Full responsibility for the editorial process for this article was delegated to another journal editor. Pablo Corral reports a relationship with Amgen Inc, AstraZeneca Pharmaceuticals LP, Merck Sharp & Dohme Corp and Novo Nordisk Inc that includes: speaking and lecture fees. Reports a relationship with Novartis Pharmaceuticals Corporation that includes: funding grants and speaking and lecture fees. Ronen Durst reports financial support was provided by Sanofi, Novartis Pharmaceuticals Corporation and Medison Pharma. Reports a relationship with Sanofi and Novartis Pharmaceuticals Corporation that includes: consulting or advisory, funding grants, and speaking and lecture fees. Reports a relationship with Medison Pharma that includes: funding grants and speaking and lecture fees. Dan Gaita reports a relationship with Amgen, AstraZeneca, Boehringer Ingelheim, Krka, Eli Lilly, Viatris, Novartis, Novo Nordisk, Pfizer, Sanofi, Servier, Zentiva. that includes: speaking and lecture fees. Daniel Gaudet reports a relationship with Amgen Inc, Eli Lilly and Company, Merck & Co Inc, Ultragenyx Pharmaceutical, Verve Therapeutics, Inc. that includes: consulting or advisory and funding grants. Reports a relationship with Arrowhead Pharmaceuticals Inc and AstraZeneca Pharmaceuticals LP that includes: consulting or advisory. Tea Gamezardashvili reports writing assistance was provided by The Georgian Atherosclerosis Association. Urh Groselj reports a relationship with Novartis Pharmaceuticals Corporation and Ultragenyx Pharmaceutical Inc and Medison Pharma that includes: speaking and lecture fees. Mariko Harada-Shiba reports a relationship with Novartis Pharmaceuticals Corporation, Amgen Inc, Ultragenyx Pharmaceutical Inc, Recordati Rare Diseases Inc, Alnylam Japan KK and Boehringer Ingelheim GmbH that includes: speaking and lecture fees. Reports a relationship with BML Inc, Medpace Inc and Protosera Inc that includes: consulting or advisory. Reports a relationship with Liid Pharmaceuticals that includes: equity or stocks. Sergio Emanuel Kaiser reports a relationship with Novartis Pharmaceuticals Corporation, Boehringer Ingelheim, Novo Nordisk, Daiichi Sankyo, Bayer, Astrazeneca that includes: board membership, consulting or advisory, and speaking and lecture fees. Gustavs Latkovskis reports a relationship with Amgen, Bayer, Novo Nordisk, Novartis that and Servier Laboratories includes: consulting or advisory, funding grants, speaking and lecture fees, and travel reimbursement. Reports a relationship with AstraZeneca, Boehringer Ingelheim, Pfizer, Roche Diagnostics, Swixx Biopharma and Zentiva that includes: speaking and lecture fees. Reports a relationship with Medpace and 89 bio that includes funding grants and with Medison Pharma that includes: travel reimbursement. Reports a relationship with MSD that includes: consulting or advisory. Vincent Maher reports financial support was provided by Novartis, Sanofi and Servier Monde. Reports a relationship with Menarini Laboratories and Novartis Ireland Ltd that includes: consulting or advisory. Winfried März reports a relationship with Amgen, Sanofi, Amryt/Chiesi Pharmaceuticals, Abbots Diagnostics, Akzea/Ionis Therapeutics, Novartis Pharma Gmbh and Sobi that includes consulting or advisory and speaking and lecture fees. Reports a relationship with DACH Society Prevention of Cardiovascular disease by serving as board member. Reports employment by SYNLAB Holding Deutchland Gmbh. Lluís Masana reports a relationship with Daiichi-Sankyo, Menarini, MSD, Novartis, Recordati, Chiesi that includes consulting or advisory, speaking and lecture fees. Adam J Nelson reports a relationship with Amgen Inc, AstraZeneca Pharmaceuticals LP, Eli Lilly and Company, Boehringer Ingelheim GmbH, Novo Nordisk Inc and Novartis Pharmaceuticals Corporation that includes: consulting or advisory and speaking and lecture fees. Stephen J Nicholls reports a relationship with AstraZeneca, NewAmsterdam Pharma, Amgen, Anthera, Cyclarity, Eli Lilly, Esperion, Novartis, Cerenis, The Medicines Company, Resverlogix, InfraReDx, Roche, Sanofi-Regeneron, and LipoScience that includes: funding grants. Reports a relationship with Abcentra, AstraZeneca, Amarin, Akcea, Eli Lilly, Anthera, Omthera, Merck, Takeda, Resverlogix, Sanofi-Regeneron, CSL Behring, Esperion, Boehringer Ingelheim, Daiichi Sankyo, Scribe Therapeutics, Silence Therapeutics, CSL Seqirus and Vaxxinity that includes that includes: consulting or advisory. Reports a relationship with NewAmsterdam Pharma NV that includes: equity or stocks. Serve as editor for Atherosclerosis. Richard C O’Brien reports a relationship with Abbott Laboratories Inc, Amgen Inc, Eli Lilly and Company and Novartis Pharmaceuticals that includes: consulting or advisory and speaking and lecture fees. Reports a relationship with AstraZeneca Pharmaceuticals LP that includes: speaking and lecture fees and a relationship with Merck & Co Inc that includes: consulting or advisory. György Paragh reports financial support was provided by Amgen Kft and Novartis Hungaria, and reports travel was provided by Gedeon Richter Plc. Arman Postadzhiyan reports a relationship with Amgen Inc, Gedeon Richter Pharma GmbH, Teva Pharmaceutical Industries Ltd, AstraZeneca Pharmaceuticals LP and Boehringer Ingelheim Pharma GmbH & Co KG that includes: speaking and lecture fees. Reports a relationship with Novartis and Servier Monde that includes: board membership and speaking and lecture fees, and reports a relationship with Novo Nordisk Inc that includes: funding grants and speaking and lecture fees. Frederick J Raal has received research grants, honoraria, or consulting fees for professional input and/or delivered lectures from Amgen, AstraZeneca, MSD, Novartis, Sanofi, Regeneron, Ultragenyx, Chiesi, Cipla, Silence Therapeutics, Verve Therapeutics, Repair Biotechnologies and LIB Therapeutics, not related to the submitted work. Reports a relationship with European Atherosclerosis Society that includes: travel reimbursement. Ximena Reyes reports a relationship with Adium, Celsius that includes: speaking and lecture fees. Erik S Stroes reports a relationship with Amsterdam UMC Location AMC that includes: consulting or advisory. Phivos Symeonides reports a relationship with Hippocrateon Private Hospital that includes: equity or stocks. Aleksandr B. Shek reports a relationship with Novartis, Menarini International Pharmaceutics, Servier Monde and Abbott that includes: speaking and lecture fees. Alberto Mello e Silva reports a relationship with Amarin, Daiichi-Sankyo, GlaxoSmithKline, Novartis, Servier, Tecnifar, Tecnimede, Viatris that includes: consulting or advisory, speaking and lecture fees, and travel reimbursement. Lale Tokgozoglu reports a relationship with Abbott, Amarin, Amgen, Astra Zeneca, Bayer, Daiichi Sankyo, Lilly, Menarini, MSD, Novartis, Novo Nordisk, Sanofi, Pfizer, Viatris, Zentiva that includes: speaking and lecture fees. Branislav Vohnout reports a relationship with Boehringer Ingelheim Pharma GmbH & Co KG that includes: consulting or advisory, funding grants, and speaking and lecture fees. Reports a relationship with KRKA Slovakia, Berlin-Chemie A Menarini SRL, Novo Nordisk and Zentiva AS that includes: funding grants and speaking and lecture fees. Reports a relationship with Novartis and Viatris Slovakia sro that includes: speaking and lecture fees. Reports a relationship with Eli Lilly that includes: board membership, consulting or advisory, and speaking and lecture fees. Reports a relationship with Amgen Europe GmbH that includes: funding grants. Luz Clemencia Zarate-Correa reports a relationship with Novartis Pharmaceuticals that includes: consulting or advisory and speaking and lecture fees. Reports a relationship with Amgen Inc, Sanofi, Chiesi Pharmaceuticals Inc, Adium Pharma SA and Pfizer Inc that includes: speaking and lecture fees. Philippe Moulin reports a relationship with CTP bio that includes: speaking and lecture fees and travel reimbursement. Reports a relationship with Swedish Orphan Biovitrum AB that includes: board membership and travel reimbursement. Reports a relationship with Biodimed that includes: consulting or advisory. Elise Evans, Marianne Benn, Shoaib Afzal, Khalid Al-Rasadi, Lambert Tetteh Appiah, Makhabbat Bekbossynova, Máxima Méndez Castillo, Mariia Cherska, Krzysztof Chlebus, Marat Ezhov, Federica Galimberti, Angel Alberto García-Peña, Anne Thushara Matthias, Ann Mertens, Olena Mitchenko, Belma Pojskic, Zaneta Petrulioniene, Ashraf Reda, Željko Reiner, Stefano Romeo, Carlos A. Aguilar Salinas, Tigist Mekonnen, Myra Tilney, Alexandros D. Tselepis(,) Margus Viigimaa declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.